Predictive value for malignancy in the finding of microcalcifications on ultrasonography of thyroid nodules.

نویسندگان

  • Maria Cristina Chammas
  • Vergilius José F de Araujo Filho
  • Raquel A Moysés
  • Marília D G Brescia
  • Grace C Mulatti
  • Lenine G Brandão
  • Giovanni G Cerri
  • Alberto R Ferraz
چکیده

BACKGROUND The aim of this study was to determine the predictive value for malignancy of microcalcifications determined by ultrasonography in thyroid nodules. METHODS One hundred seventy-seven nodules were prospectively studied by ultrasonography and compared with their fine-needle aspirative biopsy. The association between the presence and type of calcification and cytologic findings was verified through the chi-square test or likelihood ratio. RESULTS Thirty nodules showed calcification, of which 17 had fine calcifications, 3 had fine and gross calcifications, and 10 had only coarse calcification. Seven (41.18%) of 17 fine calcified nodules were malignant on cytology, 8 (47.06%) were benign, 1 (5.88%) was indeterminate, and 1 was suspect for malignancy. We found statistical significance between the presence of fine calcifications and malignancy (p = .001) and, in the 13 malignant nodule group, 8 (61.50%) had fine calcifications. CONCLUSION This study suggests that microcalcifications were highly specific for malignancy and were present in 61% of the malignant nodules.

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عنوان ژورنال:
  • Head & neck

دوره 30 9  شماره 

صفحات  -

تاریخ انتشار 2008